March 25, 1953 to June 1958
Cyril J. Ruilmann, MD

January 19, 1959 to
July 31, 1965
Joseph Baker, MD

August 1, 1965 to June 1, 1969
Nat T. Winston, Jr., MD

June 1, 1969 to July 1, 1971
Frank H. Luton, MD

July 1, 1971 to
January 17, 1975
C. Richard Treadway, MD

January 20, 1975 to
January 21, 1979
Harold W. Jordan, MD

January 22, 1979 to
March 18, 1979
C. Richard Treadway, MD
(Interim Commissioner)

April 3, 1979 to
April 15, 1984
James S. Brown, MD

May 23, 1984 to
January 16, 1987
Richard D. Sivley

January 17, 1987 to
January 18, 1991
Eric B. Taylor

January 19, 1991 to
January 21, 1995
Evelyn C. Robertson, Jr.

January 21, 1995 to
September 30, 1996
Marjorie Nelle H. Cardwell

October 1, 1996 to
March 17, 1999
Ben Dishman (Acting Commissioner)

March 18, 1999 to
January 8, 2003
Elisabeth Rukeyser

January 9, 2003 to present
Ginna Betts